Archive for the ‘causes’ Category

Causes of Memory Loss








When it comes to causes of memory loss, there are several things to consider.

The first is that it might not actually be “memory loss” but a lessening of concentration. So the “where did I leave my keys” problem we all have is not really a loss of memory but simply being distracted. And we do that from the time we’re walking until the time we stop walking. :-) The issue is (if you’re like me) you notice it more the older you get because you’re asking yourself the question, “Am I losing it?” And forgetting where you left your keys is normal. Now, if you forget where you left your keys and your car, we may need to chat.

Let’s deal with the big elephant in the room, Alzheimer’s. Memory loss is indeed one of the first symptoms of Alzheimers disease. No getting around this one, but the majority of your early concerns can’t be distinguished from normal “forgetting”.

Frontal Temporal Dementia is starting to hit the news and this may involve forgetting, it mostly involve a change in behavior in 45-65 year olds that may be mistaken for mid-life crisis or depression. There is a change in mood and behavior that may involve some forgetting of social matters. Talk to your doctor if your loved ones seem to be in this mode. It’s often misdiagnosed according to reports.

A big one for seniors is the interaction of different medications or medications all by themselves. A friend was diagnosed with a blood pressure issue and medications were prescribed. They then started to forget things and were not able to concentrate and family and friends were quite worried (it had followed a stroke). But a Net search of the mediation showed side effects similar to what they were experiencing and as soon as that medication was removed, the symptoms disappeared. Simply put the drug name (the complicated chemical name – not the sales name) into a Google search and read what pops up.

Can you rule out alcohol and drug abuse?

And when it comes to causes of memory loss, there are a wide range of physical diseases that create this condition. Unfortunately, none of them are particularly pleasant (brain tumors, fibromyalgia, meningitis, Parkinson’s, West Nile virus, thyroid problems, exposure to chemicals, and many, many more.)

The most important step is to insist on getting all the possible causes tested for if there is serious memory loss rather than accepting a quick diagnosis of dementia or Alzheimer’s disease.

Alzheimers and Beer







So the amount of beer you drink – the amount of beer belly you carry – directly correlates to the size of your brain and is correlated with Alzheimers.

Dr Sudha Seshadri – lead researcher on this study from Boston University School of Medicine measured body mass index, waist circumference, and scanning to evaluate the amount of belly fat.

The study showed (as has other studies) that as belly fat increased, brain volume decreased. But it also correlated with Alzheimers. Note the total body weight was correlated, just the amount of fat residing between internal organs (belly fat) so bigger is OK – fat is not.

So we all know that excess weight correlates highly to high blood pressure, cholesterol and diabetes; now we can add Alzheimers to that list.

One more reason to keep losing weight he says having dropped 20 pounds by exercise in the past year.

Alzheimers Dementia and Anesthetics







Researchers have demonstrated that when it comes to Alzheimers dementia and anesthetics, the use of anesthetics is now one of the causes. Alzheimers and elective surgery may be related in some populations.

There are two things you need to know.The first is that the protein amyloid-beta (short form A-beta) builds up in the brain and this is thought to be the cause of Alzheimers effect.The second thing is that it has now been shown that using anesthetics in surgery causes a buildup of A-beta in the brain.

The specific anesthetic under study is the most commonly used one called soflurane. In the study, it was quite clear that experiments in petri dishes were being replicated in the
alzheimer’s-mouse population.Indeed increased brain cell death was quite pronounced in mice that had not been treated beforehand with clioquinol (a drug that reduces the producton of A-beta).

The problem with this of course is that one study doesn’t make a trend or create a change in normal hospital practice because… well, it’s only one study.

So there’s a lot more work to be done on this.

It should also be pointed out that the mice were killed fairly shortly (in stages to 12 hours) after the exposure and that there were no long term mice past that 12 hours.There are no long term tests on humans in this regard either.

In practical terms, it is commonly known that there is a short term condition in some patients (after surgery) that resembles dementia.This passes in most people with time.
Whether it will pass with seniors or those with Alzheimers dementia seems to be the question.But in practical terms, it would seem to make common sense (and one more reason) for seniors to avoid elective surgery requiring anesthetics whenever possible,







Alzheimers and Smoking







When it comes to relating Alzheimers and smoking – it turns out that passive smoking – getting your lungs filled with smoke from spouses, co-workers or that idiot next to you has been tied into a greater chance of developing Alzheimers

Researchers at Cambridge University and Peninsula Medical School looked at the research results from a survey of approximately 5000 adults (50 years and older).

While it has been known for some time that smokers have a greater than average chance of getting Alzheimers, it now appears that non-smokers also have a greater than average chance if they inhale enough smoke. So the the workplace is as big a risk as the home in the study.

Bottom Line

So if your spouse, family member or workplace isn’t smoke free yet, you
are at risk of developing Alzheimer’s as a result.

Alzheimers Genetic Research on A673V







Now here’s interesting news about Alzheimers genetic research.

It seems that if you have one copy of the recessive gener A673V, you’re
not going to get Alzheimer’s.

But if you have two copies of it, you’re guaranteed to get it.

So a combination of these two recessive genes (and this research suggests there may be other genes that do this as well) is bad news for the nearly 10 million baby boomers that are statistically set to develop this disease over the next few years.

Note that there are already three dominant gene combinations are already known for Early onset Alzheimers but this is the first recessive combination found.

Research done by Dr. Fabrizio Tagliavini of the Carlo Besta National Neurological Institute in Milan, italy

Bottom Line:

There are no implications for treatment at this stage but it surely leads other researchers to take a fresh look at possible genetic combinations and approaches. It might be possible to develop drugs to fight off the effects of specific genetic combinations.

Causes of Dementia








There are different causes of dementia (Alzherimers is only one) and one of the main difficulties lay-people have is sorting out the differences.

For example, a quick list includes: infections, small strokes, head injuries, drug interactions or drugs by themselves and even some nutritional deficiencies. And of course, Alzheimer’s disease is included in there.

The bottom line is that anything that can influence the operation of the brain can give you symptoms of dementia. The good news is that some of these difficulties can be reversed (i.e. stop the medication or fix the nutritional deficiency) so jumping to conclusions that the dementia is permanent before the underlying cause is known
isn’t a smart thing to do (but entirely common and human given our public understanding of this disease).

A Short Summary of Causes of Dementia

Causes of Dementia You Can’t Reverse

Alzheimer ‘s Disease. This is indeed the most common cause of dementia – it is estimated that it creates 50% of the conditions. The good news is that there ‘s another 50% out there that isn’t Alzheimer ‘s. Alzheimer ‘s can be treated and slowed but is irreversible and damage is permanent.

Vascular Dementia This is the second most common cause of dementia and it is estimated to hit 30-40% of dementia patients. This is the common “hardening of the arteries” thatwe hear about so much. Deposits of fat, dead tissue etc form on the inside of our arteries and block off the blood flow to the brain. This in turn creates many mini-strokes and brain damage. There are several different forms of this dementia (all are related to blood restriction however). Treatments can (like Alzheimer ‘s) slow the progression but once a brain function is lost, it can ‘t be recovered.

Other Diseases that create or mimic dementia include:

Parkinson ‘s Disease may create some symptoms but is not the same nor will everyone who gets Parkinson ‘s develop dementia.

Lewy body dementia is caused by microscopic bits of protein which destroy nerve cells.

Huntington ‘s Disease is an inherited problem where certain kinds of brain cells waste away. Again, it ‘s not guaranteed that all those with Huntington ‘s will develop symptoms of dementia but it ‘s fairly common.

Creutzfedt-Jakob disease is a disease created by small”agents”called prions that invade and kill off brain cells. This problem develops quickly and is fatal – it tends to attack younger or middle-aged individuals.

The important thing to understand is that treatment is different for each of these problems and trying to do this yourself is next to impossible. Do see a physician for assistance

Treatable Causes of Dementia

Head Injury. Brain damage and repair has come a huge way in over the last few years. The brain will often”remap”itself if given the proper rehabilitation processes. Injuries that occur over a long time (thinking boxing or head-beating sports) may not be treatable and can lead to dementia.

Infections of the brain (meningitis, encephalitis) can be primarycauses of dementia. Treat these and the problems diminish. Other infections such as HIV/Aids and syphilis can directly influence the brain in their latter stages because of brain cell inflammation.

Brain tumors can mimic dementia. The swell and interfere with normal glandular operations so they can mimic the symptoms of dementia.

Exposure to toxins. Working around heavy metals (mercury, lead) without protection can be hazardous to your health and this is one way the problem presents itself.

Hormone problems (thyroid, pituitary) can lead to hormone imbalances and this can mimic dementia symptoms and lead to permanent damage if not treated.

Hydrocephalus or swelling of the brain (the brain”floats”in clear cerebrospinal fluid) created by an excess fluid and the resulting pressure on the inside of the head – directly influencing how the brain functions. There are several forms of this problem and all
are causes of dementia but can be reversed with the appropriate timely treatment.

Metabolic disorder of the liver, pancreas and kidneys can disrupt salt balances in the body and this in turn can (quite quickly) create conditions that mimic Alzheimers. If this persists, brain cells may die but if treated on time a full recovery is possible.

Hypoxia (lack of oxygen in the blood) is one of the treatable causes of dementia. The lack of oxygen in the blood starves the brain and can kill brain cells. Pneumonia or Emphysema are two primary causes of this problem. This is one reason why it is thought that cigarette smoking that creates

Emphysema is also related to Alzheimer ‘s.

Congestive heart problems are also related to hypoxia.

Drug reactions. I ‘m told (off the record) that this is more common that we ‘d like to know about and with the drug mixes that many seniors are on for a variety of conditions, it is impossible to track all the possible outcomes. Individual drugs – such as those for sedation can create these symptoms as can those that create symptoms such as”dry mouth”or”constipation”

This is not to mention illegal drugs such as cocaine or heroin may cause dementia symptoms if taken in high enough doses, for long times, or taken by elderly people Drug withdrawal usually removes the reaction in most cases.

Nutritional deficiencies. The B vitamins are particularly associated with symptoms that resemble dementia.

Alcoholism - chronic drinking creates liver problems and this in turn is one of the above causes of dementia

Bottom Line

When it comes to any of these causes of dementia, the rule of thumb is to work with a doctor to get a reliable diagnosis. That diagnosis is the basis for treatment and lay people simply can’t make this kind of distinction.